Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy.

BACKGROUND:Statin therapy reduces the risk of occlusive vascular events, but uncertainty remains about potential effects on cancer. We sought to provide a detailed assessment of any effects on cancer of lowering LDL cholesterol (LDL-C) with a statin using individual patient records from 175,000 pati...

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Main Authors: Cholesterol Treatment Trialists' (CTT) Collaboration, Jonathan R Emberson, Patricia M Kearney, Lisa Blackwell, Connie Newman, Christina Reith, Neeraj Bhala, Lisa Holland, Richard Peto, Anthony Keech, Rory Collins, John Simes, Colin Baigent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3261846?pdf=render