The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals

The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals

Astrocytes have critical roles in immune defense, homeostasis, metabolism, and synaptic remodeling and function in the central nervous system (CNS); however, excessive activation of astrocytes with increased intermediate filaments following neuronal trauma, infection, ischemia, stroke, and neurodege...

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Bibliographic Details
Main Authors: Libing Ye, Ying Yang, Xie Zhang, Pingtao Cai, Rui Li, Daqing Chen, Xiaojie Wei, Xuesong Zhang, Huazi Xu, Jian Xiao, Xiaokun Li, Li Lin, Hongyu Zhang
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
astrocytes
bFGF
TLR4/NFκB
GFAP
vimentin
Online Access:http://www.mdpi.com/1422-0067/17/1/37

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http://www.mdpi.com/1422-0067/17/1/37

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