Biophysical studies of cholesterol effects on chromatin[S]

Changes in chromatin structure regulate gene expression and genome maintenance. Molecules that bind to the nucleosome, the complex of DNA and histone proteins, are key modulators of chromatin structure. Previous work indicated that cholesterol, a ubiquitous cellular lipid, may bind to chromatin in v...

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Bibliographic Details
Main Authors: Isabel T.G. Silva, Vinícius Fernandes, Caio Souza, Werner Treptow, Guilherme M. Santos
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520338293