Cancer reduces transcriptome specialization.

A central goal of cancer biology is to understand how cells from this family of genetic diseases undergo specific morphological and physiological changes and regress to a de-regulated state of the cell cycle. The fact that tumors are unable to perform most of the specific functions of the original t...

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Bibliographic Details
Main Authors: Octavio Martínez, M Humberto Reyes-Valdés, Luis Herrera-Estrella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2862708?pdf=render