EGR-2 is not required for in vivo CD4 T cell mediated immune responses.

<h4>Background</h4>The zinc finger transcription factor EGR-2 has been shown to play an important role in the induction of T cell anergy and the regulation of peripheral T cell tolerance. In vitro, a prior study has show that T cells deficient in EGR-2 are hyperproliferative to IL-2 and...

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Bibliographic Details
Main Authors: Hilda E Ramón, Pedro J Cejas, David LaRosa, Adeeb Rahman, John E Harris, Jidong Zhang, Christopher Hunter, Yongwon Choi, Laurence A Turka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20886122/?tool=EBI