TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC

TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC

Tumor necrosis factor-induced protein-8 (TIPE) is highly expressed in colorectal cancer (CRC). Decoy receptor 3 (DcR3) is a soluble secreted protein that can antagonize Fas ligand (FasL)-induced apoptosis and promote tumorigenesis. It remains unclear whether TIPE can regulate DcR3 expression. In thi...

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Bibliographic Details
Main Authors: Mengya Zhong, Xingfeng Qiu, Yu Liu, Yan Yang, Lei Gu, Chenxi Wang, Huiyu Chen, Zhongchen Liu, Jiayin Miao, Guohong Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
cell proliferation
migration
apoptosis
PI3K/AKT signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.623048/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.623048/full

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