Semisynthesis, Characterization and Evaluation of New Adenosine Derivatives as Antiproliferative Agents

We describe the semisynthesis and biological effects of adenosine derivatives, which were anticipated to function as agonists for the A3 receptor. Molecular docking was used to select candidate compounds. Fifteen nucleoside derivatives were obtained through nucleophilic substitutions of the N6-posit...

Full description

Bibliographic Details
Main Authors: Francisco Valdés Zurita, Nelson Brown Vega, Margarita Gutiérrez Cabrera
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/5/1111