Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

HIV-1 envelope glycoprotein (Env) mediates the fusion of viral and target cell membranes and is a major target for HIV vaccine development. Here, the authors determine the NMR structure of a bicelle incorporated Env segment comprising the transmembrane domain (TMD) and a portion of the cytoplasmic t...

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Bibliographic Details
Main Authors: Alessandro Piai, Qingshan Fu, Yongfei Cai, Fadi Ghantous, Tianshu Xiao, Md Munan Shaik, Hanqin Peng, Sophia Rits-Volloch, Wen Chen, Michael S. Seaman, Bing Chen, James J. Chou
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16165-0

Internet

https://doi.org/10.1038/s41467-020-16165-0

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