Placental syncytium forms a biophysical barrier against pathogen invasion.

Fetal syncytiotrophoblasts form a unique fused multinuclear surface that is bathed in maternal blood, and constitutes the main interface between fetus and mother. Syncytiotrophoblasts are exposed to pathogens circulating in maternal blood, and appear to have unique resistance mechanisms against micr...

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Bibliographic Details
Main Authors: Varvara B Zeldovich, Casper H Clausen, Emily Bradford, Daniel A Fletcher, Emin Maltepe, Jennifer R Robbins, Anna I Bakardjiev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3861541?pdf=render