Enhanced survival of human-induced pluripotent stem cell transplant in parkinsonian rat brain by locally applied cyclosporine

Enhanced survival of human-induced pluripotent stem cell transplant in parkinsonian rat brain by locally applied cyclosporine

A major limitation with cell transplantation in patients is the unimpressive number of cells survived. The death of grafted cells involves apoptosis and immunorejection. In this review, we encapsulate the recent preclinical development that improves the survival of grafted cells and mitigates the im...

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Bibliographic Details
Main Authors: Michael Sheyner, Seong-Jin Yu, Yun Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Brain Circulation
Subjects:
Co-grafts
cyclosporine-A
immunorejection
nanoVeh
nanoparticles
Parkinson's disease
stem cells
trophic factors
Wharton's jelly mesenchymal stem cells
xenografts
Online Access:http://www.braincirculation.org/article.asp?issn=2394-8108;year=2019;volume=5;issue=3;spage=130;epage=133;aulast=Sheyner

Internet

http://www.braincirculation.org/article.asp?issn=2394-8108;year=2019;volume=5;issue=3;spage=130;epage=133;aulast=Sheyner

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