Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome

Objective: Psoriasis is a chronic inflammatory skin disease that is thought to affect ∼2% of the global population. Psoriasis has been associated with ∼30% increased risk of developing type 2 diabetes (T2D), with numerous studies reporting that psoriasis is an independent risk-factor for T2D, separa...

Full description

Bibliographic Details
Main Authors: Elizabeth A. Evans, Sophie R. Sayers, Xenia Kodji, Yue Xia, Mahum Shaikh, Alizah Rizvi, James Frame, Susan D. Brain, Michael P. Philpott, Rosalind F. Hannen, Paul W. Caton
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820301216