Immortalization of mouse myogenic cells can occur without loss of p16<sup><it>INK4a</it></sup>, p19<sup><it>ARF</it></sup>, or p53 and is accelerated by inactivation of Bax

Immortalization of mouse myogenic cells can occur without loss of p16<sup><it>INK4a</it></sup>, p19<sup><it>ARF</it></sup>, or p53 and is accelerated by inactivation of Bax

<p>Abstract</p> <p>Background</p> <p>Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate myotubes. Possible gene...

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Bibliographic Details
Main Authors: Kravetz Amanda J, Kostek Christine A, Girgenrath Mahasweta, Malowitz Jonathan, Nowak Jonathan A, Dominov Janice A, Miller Jeffrey
Format: Article
Language:English
Published: BMC 2004-01-01
Series:BMC Cell Biology
Subjects:
apoptosis
Bax
myoblast
muscle fiber
p16<sup><it>INK4a</it></sup>
p19<sup><it>ARF</it></sup>
p53
Online Access:http://www.biomedcentral.com/1471-2121/5/1

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http://www.biomedcentral.com/1471-2121/5/1

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