Stat1 Expression is an Independent Indicator of Prognosis in Lymph node Positive Breast Carcinomas
Introduction: STAT-1 is the main signal transducer of γIFN signalling through the IFGNR1. STAT-1 can act as a tumour suppressor by induction of the cycle inhibitors p27 and p21 and proapoptotic signals such as casapse 1. Both γIFN knockout mice and STAT-1 knockout mice show...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2005-10-01
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Series: | Iranian Journal of Public Health |
Subjects: | |
Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2472.pdf&manuscript_id=2472 |