Stat1 Expression is an Independent Indicator of Prognosis in Lymph node Positive Breast Carcinomas

Introduction: STAT-1 is the main signal transducer of γIFN signalling through the IFGNR1. STAT-1 can act as a tumour suppressor by induction of the cycle inhibitors p27 and p21 and proapoptotic signals such as casapse 1. Both γIFN knockout mice and STAT-1 knockout mice show...

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Bibliographic Details
Main Authors: Z Madjd, A Al -Atta, NFS Watson, I Spendlove, I Ellis, LG Durrant
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2005-10-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2472.pdf&manuscript_id=2472