Quantitative Structure - Activity Relationships Study of Carbonic Anhydrase Inhibitors Using Logistic Regression Model

Quantitative Structure - Activity Relationships Study of Carbonic Anhydrase Inhibitors Using Logistic Regression Model

Binary Logistic Regression (BLR) has been developed as non-linear models to establish quantitative structure- activity relationships (QSAR) between structural descriptors and biochemical activity of carbonic anhydrase inhibitors. Using a training set consisted of 21 compounds with known ki values, t...

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Bibliographic Details
Main Authors: Hassan Sahebjamee, Parichehre Yaghmaei, Parviz Abdolmaleki, Ali Reza Foroumadi
Format: Article
Language:English
Published: Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR 2013-06-01
Series:Iranian Journal of Chemistry & Chemical Engineering
Subjects:
quantitative structure-activity relationship
binary logistic regression
carbonic anhydrase inhibitors
Online Access:http://www.ijcce.ac.ir/article_5864_435196c58da6216947cb33e2c3a95785.pdf

Internet

http://www.ijcce.ac.ir/article_5864_435196c58da6216947cb33e2c3a95785.pdf

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