Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants

Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants

Mariangela Cavarelli et al. utilize cynomolgus macaque colorectal tissue explants to explore the effect of leukocytospermic seminal plasma (LSP) on SIVmac251 infection. Their results suggest that mucosal SIV infection is influenced by the inflammatory state of the semen donor, providing further insi...

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Bibliographic Details
Main Authors: Mariangela Cavarelli, Stéphane Hua, Naima Hantour, Sabine Tricot, Nicolas Tchitchek, Céline Gommet, Hakim Hocini, Catherine Chapon, Nathalie Dereuddre-Bosquet, Roger Le Grand
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02383-9

Internet

https://doi.org/10.1038/s42003-021-02383-9

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