A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.

A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.

The large nucleoporin Nup358/RanBP2 forms eight filaments that project from the nuclear pore into the cytoplasm where they function as docking platforms for nucleocytoplasmic transport receptors. RNAi screens have implicated Nup358 in the HIV-1 life cycle. The 164 C-terminal amino acids of this 3,22...

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Bibliographic Details
Main Authors: Anne M Meehan, Dyana T Saenz, Rebekah Guevera, James H Morrison, Mary Peretz, Hind J Fadel, Masakazu Hamada, Jan van Deursen, Eric M Poeschla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3930637?pdf=render

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http://europepmc.org/articles/PMC3930637?pdf=render

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