κ-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca2+/CaMKII/CREB Pathway

Objective. Cardiopulmonary bypass (CPB) is an important cardiac operation and also a high-risk procedure, leading to postoperative neurocognitive disorder. However, there are few effective drugs to treat the aftermath of CPB. Therefore, we observe the effect of kappa opioid receptor (KOR) agonist on...

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Bibliographic Details
Main Authors: Guopeng Ding, Dandan Li, Yingjie Sun, Keyan Chen, Dandan Song
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Healthcare Engineering
Online Access:http://dx.doi.org/10.1155/2021/3401654