BRCA1 Accelerates CtIP-Mediated DNA-End Resection

DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In higher eukaryotes, CtIP regulates resection by integrating cellular signals via its posttranslational modifications and protein-protein interactions, including cell-cycle-controlled i...

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Bibliographic Details
Main Authors: Andrés Cruz-García, Ana López-Saavedra, Pablo Huertas
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007682