BRCA1 Accelerates CtIP-Mediated DNA-End Resection
DNA-end resection is a highly regulated and critical step in the response and repair of DNA double-strand breaks. In higher eukaryotes, CtIP regulates resection by integrating cellular signals via its posttranslational modifications and protein-protein interactions, including cell-cycle-controlled i...
Main Authors: | Andrés Cruz-García, Ana López-Saavedra, Pablo Huertas |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014-10-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714007682 |
Similar Items
-
DNA end resection requires constitutive sumoylation of CtIP by CBX4
by: Isabel Soria-Bretones, et al.
Published: (2017-07-01) -
Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP
by: James M. Daley, et al.
Published: (2017-10-01) -
The Role of CtIP in BRCA1-Mediated Tumor Suppression
by: Reczek, Colleen Renee
Published: (2012) -
ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection.
by: Fernando Mejías-Navarro, et al.
Published: (2020-05-01) -
RB Regulates DNA Double Strand Break Repair Pathway Choice by Mediating CtIP Dependent End Resection
by: Yuning Jiang, et al.
Published: (2020-12-01)