Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells

Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells

Abstract Consumption of non-nutritive sweeteners (NNS) has been consistently associated with obesity and cardiometabolic disease in epidemiologic studies. Herein, we investigated effects of sucralose, a widely used NNS, at a cellular level. We wanted to investigate effect of sucralose on reactive ox...

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Bibliographic Details
Main Authors: Nabanita Kundu, Cleyton C. Domingues, Jay Patel, Mohammed Aljishi, Neeki Ahmadi, Mona Fakhri, Allison C. Sylvetsky, Sabyasachi Sen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Non-nutritive sweeteners
Mesenchymal stromal cells
Adipogenesis
Obesity
Diabetes
Reactive oxygen species
Online Access:http://link.springer.com/article/10.1186/s13287-020-01753-0

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http://link.springer.com/article/10.1186/s13287-020-01753-0

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