Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins

Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins

Many genes have been implicated in the underlying cause of autism but each gene accounts for only a small fraction of those diagnosed with autism. There is increasing evidence that activity-dependent changes in neuronal signaling could act as a convergent mechanism for many of the changes in synapti...

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Bibliographic Details
Main Authors: Joaquin N Lugo, Gregory D Smith, Erin P Arbuckle, Jessika eWhite, Andrew J Holley, Crina M Floruta, Nowrin eAhmed, Maribel C Gomez, Obi eOkonkwo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Anxiety
autism
Autism Spectrum Disorders
Pten
hyperactivity
Kv4.2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00027/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00027/full

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