MRI-based clinical-radiomics model predicts tumor response before treatment in locally advanced rectal cancer

MRI-based clinical-radiomics model predicts tumor response before treatment in locally advanced rectal cancer

Abstract Neoadjuvant chemo-radiotherapy (CRT) followed by total mesorectal excision (TME) represents the standard treatment for patients with locally advanced (≥ T3 or N+) rectal cancer (LARC). Approximately 15% of patients with LARC shows a complete response after CRT. The use of pre-treatment MRI...

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Bibliographic Details
Main Authors: Andrea Delli Pizzi, Antonio Maria Chiarelli, Piero Chiacchiaretta, Martina d’Annibale, Pierpaolo Croce, Consuelo Rosa, Domenico Mastrodicasa, Stefano Trebeschi, Doenja Marina Johanna Lambregts, Daniele Caposiena, Francesco Lorenzo Serafini, Raffaella Basilico, Giulio Cocco, Pierluigi Di Sebastiano, Sebastiano Cinalli, Antonio Ferretti, Richard Geoffrey Wise, Domenico Genovesi, Regina G. H. Beets-Tan, Massimo Caulo
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84816-3

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https://doi.org/10.1038/s41598-021-84816-3

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