Long‐Term Effects of Sglt2 Deletion on Bone and Mineral Metabolism in Mice

ABSTRACT Sodium‐glucose cotransporter 2 (SGLT2) inhibitors improve kidney and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). However, bone fragility has emerged as a side effect in some but not in all human studies. Because use of SGLT2 inhibitors in humans affects mineral...

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Bibliographic Details
Main Authors: Claire Gerber, Xueyan Wang, Valentin David, Susan E. Quaggin, Tamara Isakova, Aline Martin
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10526