ApoB48 as an Efficient Regulator of Intestinal Lipid Transport

Fatty meals induce intestinal secretion of chylomicrons (CMs) containing apolipoprotein (Apo) B48. These CMs travel via the lymphatic system before entering the circulation. ApoB48 is produced after post-transcriptional RNA modification by Apobec-1 editing enzyme, exclusively in the small intestine...

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Bibliographic Details
Main Authors: Chunmin C. Lo, Karen T. Coschigano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00796/full