Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development

Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development

Abstract Background The embryonic day E10–13 period of mouse heart development is characterized by robust cardiomyocyte proliferation that creates the compact zone of thickened ventricular wall myocardium. This process is initiated by the formation of the epicardium on the outer heart surface, which...

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Bibliographic Details
Main Authors: Kai Wang, Hua Shen, Peiheng Gan, Susana Cavallero, S. Ram Kumar, Ching-Ling Lien, Henry M. Sucov
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Developmental Biology
Subjects:
Heart development
Epicardium
IGF2
IGF1R
Insulin receptor
Cardiomyocyte proliferation
Online Access:http://link.springer.com/article/10.1186/s12861-019-0186-8

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http://link.springer.com/article/10.1186/s12861-019-0186-8

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