Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development
Abstract Background The embryonic day E10–13 period of mouse heart development is characterized by robust cardiomyocyte proliferation that creates the compact zone of thickened ventricular wall myocardium. This process is initiated by the formation of the epicardium on the outer heart surface, which...
Main Authors: | Kai Wang, Hua Shen, Peiheng Gan, Susana Cavallero, S. Ram Kumar, Ching-Ling Lien, Henry M. Sucov |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | BMC Developmental Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12861-019-0186-8 |
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