Novel Cinnamic Acid Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Modeling Studies

Novel Cinnamic Acid Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Modeling Studies

Cinnamic acids have been identified as interesting compounds with antioxidant, anti-inflammatory and cytotoxic properties. In the present study, simple cinnamic acids were synthesized by Knoevenagel condensation reactions and evaluated for the above biological activities. Compound 4ii proved to be t...

Full description

Bibliographic Details
Main Authors: Eleni Pontiki, Dimitra Hadjipavlou-Litina, Konstantinos Litinas, George Geromichalos
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
antioxidant activity
inflammation
cancer
lipoxygenase
cinnamic acids
molecular docking
Online Access:http://www.mdpi.com/1420-3049/19/7/9655

Internet

http://www.mdpi.com/1420-3049/19/7/9655

Similar Items