Generating Recombinant Antibodies to Membrane Proteins through Phage Display

Generating Recombinant Antibodies to Membrane Proteins through Phage Display

One of the most important classes of proteins in terms of drug targets is cell surface membrane proteins, and yet it is a challenging set of proteins for generating high-quality affinity reagents. In this review, we focus on the use of phage libraries, which display antibody fragments, for generatin...

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Bibliographic Details
Main Authors: Renhua Huang, Margaret M. Kiss, Melissa Batonick, Michael P. Weiner, Brian K. Kay
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Antibodies
Subjects:
affinity selection
fragments of antigen binding (Fabs)
G-protein coupled receptors (GPCRs)
membrane proteins
nanodiscs
phage-display
recombinant antibodies
single-domain antibodies
transfection
virus-like particles (VLPs)
Online Access:http://www.mdpi.com/2073-4468/5/2/11

Internet

http://www.mdpi.com/2073-4468/5/2/11

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