A polymeric diet rich in transforming growth factor beta 2 does not reduce inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal rats

A polymeric diet rich in transforming growth factor beta 2 does not reduce inflammation in chronic 2,4,6-trinitrobenzene sulfonic acid colitis in pre-pubertal rats

Abstract Background Pediatric Crohn’s disease is characterized by a higher incidence of complicated phenotypes. Murine models help to better understand the dynamic process of intestinal fibrosis and test therapeutic interventions. Pre-pubertal models are lacking. We aimed to adapt a model of chronic...

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Bibliographic Details
Main Authors: Claire Dupont-Lucas, Rachel Marion-Letellier, Mathilde Pala, Charlène Guerin, Asma Amamou, Marine Jarbeau, Christine Bôle-Feysot, Lionel Nicol, Amelyne David, Moutaz Aziz, Elodie Colasse, Céline Savoye-Collet, Guillaume Savoye
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Gastroenterology
Subjects:
Transforming growth factor beta 2
Fibrosis
Inflammation
Growth and development
Online Access:https://doi.org/10.1186/s12876-020-01574-8

Internet

https://doi.org/10.1186/s12876-020-01574-8

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