A direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosome.

The centrosome is the primary microtubule organizing centre of the cell. gamma-tubulin is a core component of the centrosome and is required for microtubule nucleation and centrosome function. The recruitment of gamma-tubulin to centrosomes is mediated by its interaction with NEDD1, a WD40-repeat co...

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Bibliographic Details
Main Authors: Jantina A Manning, Sonia Shalini, Joanna M Risk, Catherine L Day, Sharad Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20224777/?tool=EBI