Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects

Epigenetic regulation may contribute to the beneficial effects of physical activity against age-related neurodegeneration. For example, epigenetic alterations of the gene encoding for α-synuclein (SNCA) have been widely explored in both brain and peripheral tissues of Parkinson’s disease samples. Ho...

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Bibliographic Details
Main Authors: Simona Daniele, Barbara Costa, Deborah Pietrobono, Chiara Giacomelli, Caterina Iofrida, Maria Letizia Trincavelli, Jonathan Fusi, Ferdinando Franzoni, Claudia Martini
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/3740345