Spatial UBE2N protein expression indicates genomic instability in colorectal cancers

Abstract Background One major hallmark of colorectal cancers (CRC) is genomic instability with its contribution to tumor heterogeneity and therapy resistance. To facilitate the investigation of intra-sample phenotypes and the de novo identification of tumor sub-populations, imaging mass spectrometry...

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Bibliographic Details
Main Authors: Timo Gemoll, Elena Miroll, Oliver Klein, Annette Lischka, Murat Eravci, Christoph Thorns, Jens K. Habermann
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-019-5856-1