Cellular and viral factors regulating Merkel cell polyomavirus replication.

Cellular and viral factors regulating Merkel cell polyomavirus replication.

Merkel cell polyomavirus (MCV), a previously unrecognized component of the human viral skin flora, was discovered as a mutated and clonally-integrated virus inserted into Merkel cell carcinoma (MCC) genomes. We reconstructed a replicating MCV clone (MCV-HF), and then mutated viral sites required for...

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Bibliographic Details
Main Authors: Huichen Feng, Hyun Jin Kwun, Xi Liu, Ole Gjoerup, Donna B Stolz, Yuan Chang, Patrick S Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3142164?pdf=render

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http://europepmc.org/articles/PMC3142164?pdf=render

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