Comparison of Three Molecular Simulation Approaches for Cyclodextrin-Ibuprofen Complexation

Cyclodextrins are widely used for the solubilisation of poorly soluble drugs in the formulations. However, current cyclodextrin formulation development strongly depends on trial-and-error in the laboratory, which is time-consuming and high cost. The aim of this research was to compare three modeling...

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Bibliographic Details
Main Authors: Runmiao Wang, Hui Zhou, Shirley W. I. Siu, Yong Gan, Yitao Wang, Defang Ouyang
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2015/193049