Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells
Abstract Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially increase the expansion and activation of CD8+ T cells by targeting CD4+ T cells. When autologous OCs were used t...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-11-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-76702-1 |