Metabolic engineering of Saccharomyces cerevisiae for caffeine and theobromine production.

Caffeine (1, 3, 7-trimethylxanthine) and theobromine (3, 7-dimethylxanthine) are the major purine alkaloids in plants, e.g., tea (Camellia sinensis) and coffee (Coffea arabica). Caffeine is a major component of coffee and is used widely in food and beverage industries. Most of the enzymes involved i...

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Bibliographic Details
Main Authors: Lu Jin, Mohammad Wadud Bhuiya, Mengmeng Li, XiangQi Liu, Jixiang Han, WeiWei Deng, Min Wang, Oliver Yu, Zhengzhu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136831?pdf=render