Pleiotropic Roles of P2X7 in the Central Nervous System

The purinergic receptor P2X7 is expressed in neural and immune cells known to be involved in neurological diseases. Its ligand, ATP, is a signaling molecule that can act as a neurotransmitter in physiological conditions or as a danger signal when released in high amount by damaged/dying cells or act...

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Bibliographic Details
Main Authors: Jean M. Kanellopoulos, Cécile Delarasse
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ATP
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00401/full