Comparison of methods to quantify inducible HIV-1 outgrowth

The quantitative viral outgrowth assay (qVOA) is the gold standard for measuring inducible, replication-competent HIV-1. Using MOLT4-R5 and SupT1-R5 cell lines instead of allogeneic blasts and HIV-1 RNA detection rather than p24 enzyme-immunoassay (EIA) has been proposed to improve the sensitivity o...

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Bibliographic Details
Main Authors: P. Nathan Enick, Joseph P. Brooker, Camille M. Tumiotto, Brittany T. Staines, Joseph J. Eron, Deborah K. McMahon, Rajesh T. Gandhi, John W. Mellors, Michele D. Sobolewski
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Journal of Virus Eradication
Subjects:
HIV
RNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664021000169