Blood M2a monocyte polarization and increased formyl peptide receptor 1 expression are associated with progression from latent tuberculosis infection to active pulmonary tuberculosis disease

Blood M2a monocyte polarization and increased formyl peptide receptor 1 expression are associated with progression from latent tuberculosis infection to active pulmonary tuberculosis disease

Objectives: This study aims to explore the role of M2a polarization and formyl peptide receptor (FPR) regulation in the reactivation of Mycobacterium tuberculosis (Mtb) infection. Methods: M1/M2a monocyte percentage and FPR1/2/3 protein expression of blood immune cells were measured in 38 patients w...

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Bibliographic Details
Main Authors: Yung-Che Chen, Yu-Ping Chang, Chang-Chun Hsiao, Chao-Chien Wu, Yi-Hsi Wang, Tung-Ying Chao, Sum-Yee Leung, Wen-Feng Fang, Chiu-Ping Lee, Ting-Ya Wang, Po-Yuan Hsu, Meng-Chih Lin
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:International Journal of Infectious Diseases
Subjects:
Active tuberculosis disease
Latent tuberculosis infection
M1 monocyte
M2a polarization
Formyl peptide receptor1/2/3
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220317240

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http://www.sciencedirect.com/science/article/pii/S1201971220317240

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