miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development

miRNA miR-21 Is Largely Dispensable for Intrathymic T-Cell Development

Development of T cells in the thymus is tightly controlled to continually produce functional, but not autoreactive, T cells. miRNAs provide a layer of post-transcriptional gene regulation to this process, but the role of many individual miRNAs in T-cell development remains unclear. miR-21 is promine...

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Bibliographic Details
Main Authors: Heike Kunze-Schumacher, Samantha J. Winter, Esther Imelmann, Andreas Krueger
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
miRNA
miR-21
thymus
T cells
development
selection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02497/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02497/full

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