A new prodrug and bioactivity evaluation of methotrexate based on Chitosan

Methotrexate (MTX) is the most important drug used in the treatment of several kinds of cancers, such as colon cancer. However, this drug can cause a reduction in the target tissue bioavailability. It is administered orally and absorbed quickly. This study aimed to produce an anti-colon cancer prodr...

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Bibliographic Details
Main Authors: Mohsin Omar Mohammed, Hameed Madlool Mohammed Alkubaisi, Nadia Qader Haj
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020310677