Architecture and expression of the Nfatc1 gene in lymphocytes

Architecture and expression of the Nfatc1 gene in lymphocytes

In lymphocytes, the three NFAT factors NFATc1 (also designated as NFAT2), NFATc2 (NFAT1) and NFATc3 (NFAT4 or NFATx) are expressed and are targets of immune receptor signals which lead to a rapid rise of intracellular Ca++, the activation of phosphatase calcineurin and to activation of cytosolic NFA...

Full description

Bibliographic Details
Main Authors: Ronald eRudolf, Rhoda eBusch, Amiya Kumar Patra, Khalid eMuhammad, Andris eAvots, Jean-Christophe eAndrau, Stefan eKlein-Hessling, Edgar eSerfling
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Immunology
Subjects:
Chromatin
Lymphocytes
epigenetics
gene
Epigenetics Mechanisms of Plasticity
Histone Modifications
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00021/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00021/full

Similar Items