A Filtering Method for Identification of Significant Target mRNAs of Coexpressed and Differentially Expressed MicroRNA Clusters

MicroRNA (miRNA) binding is primarily based on sequence, but structure-specific binding is also possible. Various prediction algorithms have been developed for predicting miRNA target genes; the results, however, have relatively high levels of false positives, and the degree of overlap between predi...

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Bibliographic Details
Main Authors: Su Yeon Lee, Soo-Yong Shin, Young Jo Yoon, Yu Rang Park
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Healthcare Engineering
Online Access:http://dx.doi.org/10.1155/2018/4932904