Performance analysis of novel toxin-antidote CRISPR gene drive systems

Performance analysis of novel toxin-antidote CRISPR gene drive systems

Abstract Background CRISPR gene drive systems allow the rapid spread of a genetic construct throughout a population. Such systems promise novel strategies for the management of vector-borne diseases and invasive species by suppressing a target population or modifying it with a desired trait. However...

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Bibliographic Details
Main Authors: Jackson Champer, Isabel K. Kim, Samuel E. Champer, Andrew G. Clark, Philipp W. Messer
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Biology
Subjects:
Gene drive
Confined
Modeling
Toxin-antidote
CRISPR
Population modification
Online Access:http://link.springer.com/article/10.1186/s12915-020-0761-2

Internet

http://link.springer.com/article/10.1186/s12915-020-0761-2

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