Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease

Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is one of the most common metabolic disorder diseases, which include a histological spectrum of conditions ranging from simple steatosis to non-alcoholic steatohepatitis (NASH). Dysregulated metabolism of sphingomyelin in the liver plays a critical role in t...

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Bibliographic Details
Main Authors: Meng Jiang, Chun Li, Qiaoshu Liu, Aimin Wang, Minxiang Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Endocrinology
Subjects:
ceramide
NAFLD
NASH
apoptosis
myriocin
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00665/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00665/full

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