Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1).

Naturally acquired clinical immunity to Plasmodium falciparum is partly mediated by antibodies directed at parasite-derived antigens expressed on the surface of red blood cells which mediate disease and are extremely diverse. Unlike children, adults recognize a broad range of variant surface antigen...

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Bibliographic Details
Main Authors: James Tuju, Margaret J Mackinnon, Abdirahman I Abdi, Henry Karanja, Jennifer N Musyoki, George M Warimwe, Evelyn N Gitau, Kevin Marsh, Peter C Bull, Britta C Urban
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007870