Post-transcriptional regulation of the human reduced folate carrier as a novel adaptive mechanism in response to folate excess or deficiency
The RFC (reduced folate carrier) is the principal mechanism by which folates and clinically used antifolates are delivered to mammalian cells. hRFC (human RFC) is subject to complex transcriptional controls and exists as homo-oligomer. To explore the post-transcriptional regulation of hRFC by exoge...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Portland Press, Biochemical Society
2014-08-01
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| Series: | Bioscience Reports |
| Subjects: | |
| Online Access: | http://www.bioscirep.org/bsr/034/e130/bsr034e130.htm |