Over-expression of DSCR1 protects against post-ischemic neuronal injury.

Over-expression of DSCR1 protects against post-ischemic neuronal injury.

The Down syndrome candidate region 1 (DSCR1) gene is located on human chromosome 21 and its protein is over-expressed in brains of Down syndrome individuals. DSCR1 can modulate the activity of calcineurin, a phosphatase abundant in the brain, but its influence on stroke outcome is not clear. We comp...

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Bibliographic Details
Main Authors: Vanessa H Brait, Katherine R Martin, Alicia Corlett, Brad R S Broughton, Hyun Ah Kim, John Thundyil, Grant R Drummond, Thiruma V Arumugam, Melanie A Pritchard, Christopher G Sobey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3483156?pdf=render

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http://europepmc.org/articles/PMC3483156?pdf=render

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