Apolipoprotein A1 mimetic peptide ATI-5261 reverses arterial stiffness at late pregnancy and early postpartum in a COMT−/− mouse model of preeclampsia

Apolipoprotein A1 mimetic peptide ATI-5261 reverses arterial stiffness at late pregnancy and early postpartum in a COMT−/− mouse model of preeclampsia

Abstract Background Preeclampsia (PE) is a serious maternal complication during pregnancy. Associated arterial stiffness in PE patients leads to increased risks of cardiovascular diseases later in life. Cholesterol efflux capacity, especially ATP binding cassette transporter A1 (ABCA1) dependent cap...

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Bibliographic Details
Main Authors: Shutan Liao, Hao Wu, Ruiying Chen
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Clinical Hypertension
Subjects:
Apolipoprotein A1
Arterial stiffness
Mice
Preeclampsia
Cholesterol efflux
Pulse wave velocity
Online Access:http://link.springer.com/article/10.1186/s40885-018-0097-1

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http://link.springer.com/article/10.1186/s40885-018-0097-1

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