Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles

Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles

Recently, various immunosuppressant drugs have been shown to induce hair growth in normal hair as well as in alopecia areata and androgenic alopecia; however, the responsible mechanism has not yet been fully elucidated. In this study, we investigate the influence of mycophenolate (MPA), an immunosup...

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Bibliographic Details
Main Authors: Sunhyo Ryu, Yonghee Lee, Moo Yeol Hyun, Sun Young Choi, Kwan Ho Jeong, Young Min Park, Hoon Kang, Kui Young Park, Cheryl A. Armstrong, Andrew Johnson, Peter I. Song, Beom Joon Kim
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
MPA
β-catenin
GSK3β
DKK-1
IFN-γ
TGF-β2
dermal papilla cell
hair growth
Online Access:http://www.mdpi.com/1422-0067/15/9/16800

Internet

http://www.mdpi.com/1422-0067/15/9/16800

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